Outcome Modulation Across Tasks in the Primate Dorsolateral Prefrontal Cortex
نویسندگان
چکیده
منابع مشابه
Dopaminergic modulation of short-term synaptic plasticity in fast-spiking interneurons of primate dorsolateral prefrontal cortex.
Dopaminergic regulation of primate dorsolateral prefrontal cortex (PFC) activity is essential for cognitive functions such as working memory. However, the cellular mechanisms of dopamine neuromodulation in PFC are not well understood. We have studied the effects of dopamine receptor activation during persistent stimulation of excitatory inputs onto fast-spiking GABAergic interneurons in monkey ...
متن کاملModulation of Drug Craving in Crystalline-Heroin Users by Transcranial Direct Current Stimulation of Dorsolateral Prefrontal Cortex
Background: Drug craving, the main cause of relapse and a major motivator for drug use, is a challenging obstacle in substance use treatment. Transcranial direct current stimulation (tDCS), a non-invasive neuromodulatory technique, has shown promising outcomes in treating different neuropsychiatric disorders such as drug addiction, more specifically on drug craving. The aim in the current study...
متن کاملOrbital Versus Dorsolateral Prefrontal Cortex
Content differentiation models posit that different areas of the prefrontal cortex perform similar operations but differ in terms of the content that is operated on. For example, it has been suggested that the orbitofrontal cortex (OFC) and the dorsolateral prefrontal cortex (DLPFC) perform similar working memory or inhibitory operations, but on different types of content (e.g., reward versus s...
متن کاملCholinergic modulation of working memory activity in primate prefrontal cortex.
The prefrontal cortex, a cortical area essential for working memory and higher cognitive functions, is modulated by a number of neurotransmitter systems, including acetylcholine; however, the impact of cholinergic transmission on prefrontal activity is not well understood. We relied on systemic administration of a muscarinic receptor antagonist, scopolamine, to investigate the role of acetylcho...
متن کاملAssociation of storage and processing functions in the dorsolateral prefrontal cortex of the nonhuman primate.
The prominent role of the prefrontal cortex (PFC) in working memory (WM) is widely acknowledged both in nonhuman primates and in humans. However, less agreement exists on the issue of functional segregation within different subregions of the PFC with regard to the domains of spatial and nonspatial processing or involvement in simpler versus more complex aspects of WM, e.g., maintenance versus p...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Neuroscience
سال: 2018
ISSN: 0306-4522
DOI: 10.1016/j.neuroscience.2017.11.019